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This is taken from Winchesters site. Using their Automated Ballistics Calculator. The bullets are all 150 grain power points...in 270, 308 and 30-06..

Muzzle Muzzle Bullet
Velocity 100 200 300 400 500 Energy 100 200 300 400 500 Drop 100 200 300 400 500

270...... ....2850 2585 2335 2099 1877 1672 / 2703 2223 1814 1466 1173 930 / 0 3.7 13.8 31.9 59.8

30-06 ......2920 2607 2314 2041 1788 1558 / 2837 2261 1782 1386 1063 808 / 0 3.6 13.8 32.3 61.9

308............2820 2513 2227 1960 1713 1492 /2646 2102 1650 1278 977 741 / 0 4.0 15.1 35.3 67.4

This comparison will give you a more factual based look at different ranges and ballistics on all rifles firing the same weight bullet in it's own caliber. However....These bullets tho are NOT the best choice for optimum ballistics....they'll be much better when the BC of the bullet is higher...like the Accubond, TTSX, Ballistic Tip, SST...etc...Just changing the bullet tip to give you a better BC will give you better ballistics and downrange performance.
 
The reason I chose the grains I did was because who buys 30-06 in 150gr for moose? Most use 180 or 220, however th 220 data wasn't available on the chart I'm refering too.

Even using the Winchester data from above, it's pretty clear they are all very close in strength.
 
That's why I said

....However....These bullets tho are NOT the best choice for optimum ballistics....they'll be much better when the BC of the bullet is higher...like the Accubond, TTSX, Ballistic Tip, SST...etc...Just changing the bullet tip to give you a better BC will give you better ballistics and downrange performance..

Our moose was taken with a 140 gr bullet out of a 270 WSM...the regular 270 win had 140 Failsafes sittin in the mag just waiting
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The 270 slinging 150 grainers outperforms both the 06 and the 08 at anything over 200 yards!
 
I know we're really splitting hairs here when we're down to comparing the Ballistic Coefficient not only between calibers, but between bullet types of the same caliber and weight. The BC is basically a measure of how streamlined a bullet is as it slices through the air. Boattail versus flat bottomed tips; pointed tips versus round nose, etc.
good info here: http://www.chuckhawks.com/bc.htm

KEVINS post #19 I found most interesting, describing how different bullet designs act on (simulated) flesh.
 
BC makes all the diff in the world especially... if you like to shoot big game or targets beyond 200yds. Below is from the same article by Chuck Hawks....look at the diff in those 3 100 grain bullets...look at the drop difference between the round nose and the BT at 500 yds....18 INCHES!!.....that's JUST because of a better BC
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For example, a Hornady 100 grain round nose 6mm bullet has a BC of .216; a Hornady 100 grain spire point 6mm bullet has a BC of .357, and a Hornady 100 grain boat tail spire point 6mm bullet has a BC of .400. All three of these bullets have a sectional density (which is the ratio of a bullet's diameter to its weight) of .242, because they are all .243" in diameter and weigh 100 grains. But the more streamlined bullets have a higher ballistic coefficient. They are the ones to choose for long range shooting where a flatter trajectory is important.
To illustrate the practical difference between these three styles of bullets, let's use Hornady's trajectory figures for the 100 grain 6mm bullets above. Starting all three bullets at a muzzle velocity of 3100 fps from a scoped 6mm rifle zeroed at 300 yards, the trajectories are as follows.

.243" 100 grain Round Nose (BC .216): -1.5" @ muzzle, +4.8" @ 100 yards, +6" @ 200 yards, 0 at 300 yards, -15.9" @ 400 yards, -46" @ 500 yards.
.243" 100 grain Spire Point (BC .357): -1.5" @ muzzle, +3.8" @ 100 yards, +4.7" @ 200 yards, 0 @ 300 yards, -11.1" @ 400 yards, -30.5" @ 500 yards.
.243" 100 grain Spire Point BT (BC .400): -1.5" @ muzzle, +3.6" @ 100 yards, +4.4" @ 200 yards, 0 @ 300 yards, -10.4" @ 400 yards, -28.6" @ 500 yards.
 
I use a .300 Winchester Magnum for moose and deer hunting. For deer it is a little much, and like was already said, it either 1) doesn't expand much when you hit the ribcage or 2) it explodes like a grenade if you hit the shoulder bone. It kills deer well but I wouldn't be surprised if the other calibers mentioned do a better job at lower velocities like the 30 '06 or .308 in terms of expansion. The .300 does perform extremely well at obliterating lung, heart and liver tissue. A neck shot that hits muscle and not the spine would likely just pass through with a small .30 caliber hole so I would avoid neck shots. The .308, .270, 30-06, and 7mm Rem Mag are all excellent rifles for deer or bear.

Many will not agree but for me the .300 Win magnum is the only caliber listed that I would use (if I had the choice) for moose. In fact a .338 magnum or .375 H&H would be a better choice when that big trophy bull shows up, based on my personal experience. With those calibers the moose goes at most twenty yards when well hit.
 
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